Urinary cytology has become an essential element in the diagnosis and management of transitional cell carcinoma(TCC) of the urinary tract. lt has the advantage of being noninvasive, inexpensive, and easily accessible. Besides that
it
can
even detect malignancy when unsuspected at cystoscopy. We report a retrospective review of urine cytology in the diagnosis of 83 TCC cases that underwent 295 cytology evaluation. All patients had biopsy-proven TCC of the bladder,
ureter
and renal pelvis. The overall incidence of the positive cytology cases was 66.2%. To define the cytologic features of tumor cells, we tried to use three cytologic gradings such as "grade 1" "grade 2" and "grade 3" according to the
cytologic
degree of anaplastic neoplastic cells. These cytologic degree of anaplastic neoplastic cells. These cytologic gades of TCC were relatively well correlated with the histologic grade and tumor invasiveness. This result suggests that the
recognition
of characteristic cellular features of TCC can suspect the histologic grade and tumor stage. The false negative TCC cases were 78.9%. They showed severe inflammatory or bloody background and a few neoplastic cells. Therefore, a
cautions
approach for accurate interpretation, personal experience, and proper fixation and processing could expand the role of urinary cytology.
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